Kidney replacement therapy: Pros and Cons

Kidney replacement therapy (KRT) is a term used to encompass life-supporting treatments for kidney failure. except transplantation replaces nonendocrine functions in patients with Researchers have noted that dialysis, which one of the most common KRT used, cannot compensate all tasks performed by kidney, and thus ‘Kidney support therapy’ has been suggested be better name. Support function modern times encompasses wide array methods clinical scenarios, from ambulatory patient critically ill. The ability safely routinely deliver ongoing organ outpatient setting has, until recently, separated other support. can applied intermittently or continuously using extracorporeal (hemodialysis) Para corporeal (peritoneal dialysis) methods. All modalities exchange solute remove fluid blood, dialysis filtration across permeable membranes. Nearly 4 million people world are living on therapy(KRT),and haemodialysis (HD) remains commonest form KRT, accounting forapproximately 69% 89% dialysis. Continuous although costly mainly hemodynamically unstable patients; benefits over intermittent improved tolerability as result slower removal water. ultimate step end stage failure management, it native completely. main disadvantages relate to: Catheter related complications – blood loss, disconnection, infection access, mechanical circuit, fluctuations salt-water balance, activation coagulation cascade. Specific peritoneal include: peritonitis, catheter- associated infections, hyperglycemia, protein loss etc. Current trends artificial research lofty goal small device, preferably implanted little no maintenance required wearer would safe highly effective renal including metabolic endocrine functions. Bangladesh J Medicine 2023; Vol. 34, No. 2(1) Supplement: 181